Constantine is a historian of the early modern Netherlands and the Mediterranean primarily interested in cross-cultural encounters. His dissertation examines European-Ottoman relations between the 1590s and the 1760s. It focuses on a set of key diplomatic practices—gift-giving, ambassadorial rituals, translation, and record-keeping—to compensate for archival silences produced in the context of trans-imperial communication.
He holds a BA in History & Archaeology from the Aristotle University of Thessaloniki, an MA in Colonial & Global History and an MA in Middle Eastern & Turkish Studies, both from Leiden University where he was an Onassis Scholar. His published work to date has focused on diplomacy and captivity in the early modern Mediterranean, as well as the role of cross-confesional networks in the making of Dutch commercial primacy in the seventeenth century. His research interests further include maritime history and the history of news.